Urinary kidney injury molecule-1 rapid test predicts acute kidney injury in extremely low-birth-weight neonates

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High urinary excretion of kidney injury molecule-1 predicts adverse outcomes in acute kidney injury: a case control study

BACKGROUND Acute kidney injury (AKI) is a common clinical syndrome with poor prognosis. The insensitivity and non-specificity of traditional markers of renal dysfunction prevent timely estimation of the severity of renal injury, and the administration of possible therapeutic agents. Urinary kidney injury molecule-1 (uKIM-1) is a marker of epithelial injury of renal tubules. Different uKIM-1 lev...

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Peritoneal dialysis in an extremely low-birth-weight infant with acute kidney injury

Critically ill neonates are at high risk for acute kidney injury (AKI). Renal supportive therapy (RST) can be an important tool for supporting critically ill neonates with AKI, particularly in cases of oliguria and fluid overload. There are few reports of RST for management of oligo-anuric AKI in the extremely low-birth-weight infant weighing <1000 g. We report successful provision of peritonea...

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Incidence and outcomes of acute kidney injury in extremely-low-birth-weight infants

BACKGROUND Acute kidney injury (AKI) is a common event in the neonatal intensive care unit (NICU), especially in extremely-low-birth-weight (ELBW) infants. This cohort study investigated the incidence of and risk factors for AKI in ELBW infants and their overall survival at the postmenstrual age (PMA) of 36 weeks. METHODS All ELBW infants admitted to our NICU between January 2010 and December...

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Diagnostic Value of Urinary Kidney Injury Molecule 1 for Acute Kidney Injury: A Meta-Analysis

BACKGROUND Urinary Kidney Injury Molecule 1 (KIM-1) is a proximal tubular injury biomarker for early detection of acute kidney injury (AKI), with variable performance characteristics depending on clinical and population settings. METHODS Meta-analysis was performed to assess the diagnostic value of urinary KIM-1 in AKI. Relevant studies were searched from MEDLINE, EMBASE, Pubmed, Elsevier Sci...

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Acute Kidney Injury in Infants and Neonates

Context: AKI in neonates and infants is associated with significant morbidity and mortality. Aims: To evaluate epidemiology, clinical profile and outcomes of acute kidney injury in neonates and infants. Settings and Design: Prospective observational study from over 1year period. Methods and Material: Neonates and infants with clinical symptoms or abnormal laboratory parameters suggesting acute ...

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ژورنال

عنوان ژورنال: Pediatric Research

سال: 2015

ISSN: 0031-3998,1530-0447

DOI: 10.1038/pr.2015.125